Mouse C-C Chemokine Receptor Type 2, CCR2 ELISA Kit , 96T Monoclonal Antibodies Additional isoforms produced by alternative
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Mouse C-C Chemokine Receptor Type 2, CCR2 ELISA Kit , 96T Monoclonal Antibodies Additional isoforms produced by alternativeKey functional receptor for CCL2 but can also bind CCL7 and CCL12 chemokines (PubMed: 8631787, PubMed: 8662823, PubMed: 8996246). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (By similarity). Also acts as a receptor for the beta defensin DEFB106A DEFB106B (By similarity). Regulates the expression of T cell
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